Natural Products Alert

NAPRALERT is now offering limited free searches of the database, as well as advancing several levels of fee-based services to the natural product community, including the employment of query structures that users of our former website will be familiar with. The new NAPRALERT platform accommodates two query levels.
  • Free (with limitations) searching of the NAPRALERT database
    Includes: Organism, Pharmacology, Compound and Author-based queries.
  • Fee-based searches, charged by number of citations generated.
NCI/NIH Natural Products Information System
The National Cancer Institute (NCI) at the NIH maintains the Physician Data Query (PDQ), a comprehensive database of with cancer information summaries about Integrative, Alternative, and Complementary Therapies. The information is free to use. Summaries are designed for both healthcare professionals and patients and are reviewed and updated constantly to reflect findings from recent research.
From time to time we will announce additional search parameters and other information on NAPRALERT. Complex searches can be carried out by NAPRALERT staff. NAPRALERT exists only through user fees and tax-free contributions by those interested in seeing the database be expanded and continued. Please e-mail NAPRALERT staff for more information.


NAPRALERTĀ® is a relational database of natural products, including ethnomedical information, pharmacological/biochemical information on extracts of organisms in vitro, in situ, in vivo, in human (case reports, non-clinical trials) and clinical studies. Similar information is available for secondary metabolites from natural sources.

To date more than 200,000 scientific papers and reviews are included in NAPRALERT, representing organisms from all countries of the world, including marine and microorganisms. About 25% of the database is derived from abstracts and 75% from original articles.

We believe that our coverage of the literature is comprehensive from at least 1975 through 2004. Due to budgetary constraints, we estimate the database to currently include only about 20% of the global natural-products literature from 2005 to the present, but we are committed to becoming up-to-date in in the near future, and are currently implementing enhancements that will allow us to streamline and expedite the data-entry process. Stay tuned for further enhancements of the NAPRALERT query process that will be of interest and relevance to the end-user.

Our coverage of the literature in the following areas is quite comprehensive:

  • Clinical studies of natural products (including safety)
  • Natural products that affect sugar metabolism
  • Natural products that affect mammalian reproduction
  • Extracts and compounds that affect cancer growth
  • Natural products and antiviral (including HIV/AIDS) activity
  • Natural products and antitubercular activity
  • Natural products and tropical diseases
  • Ethnomedical information on more than 20,000 species of plants
  • Metabolism and pharmacokinetics
  • Natural products that affect plant growth
  • Review articles on organisms at the genus and/or species levels and reviews of secondary metabolites (Citations only)
  • Chemoprevention with natural products
  • Natural insecticides
  • Antiinflammatory activity of natural products
  • Analgesic activity of natural products
  • Plant growth stimulators and inhibitors
To learn more about the life and work of Norman R. Farnsworth, founder of NAPRALERT, please visit the Professor Norman Farnsworth memorial page. Norman R. Farnsworth